Am J Emerg Med 13 (1995): 536-7, 41. Like all medicines, propranolol can cause side effects, although not everyone gets them. N Engl J Med 300 (1979): 191-3, 24. Propranolol side effects. difficulty having an orgasm. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to propranolol: intravenous solution, oral capsule extended release, oral concentrate, oral liquid, oral solution, oral tablet, Common (1% to 10%): Hypotension, cold extremities, Raynaud's phenomenon, Uncommon (0.1% to 1%): Heart failure, precipitation of heart block, Rare (less than 0.1%): Exacerbation of claudication, postural hypotension (which may be associated with syncope), Frequency not reported: Bradycardia, congestive heart failure[Ref]. Although not all of these side effects may occur, if they do occur they may need medical attention. If you are concerned at all, speak to your doctor or pharmacist for advice. Shand DG "Propranolol." Often side effects improve as your body gets used to the new medicine. In one case, electrical alternans was clearly not rate-related (since it occurred during propranolol therapy at a slower rate than the patient's "native" ventricular tachycardia) and was associated with echocardiographically-demonstrated mechanical alternans. Inderide (propranolol hydrochloride and hydrochlorothiazide) is a combination of a beta-blocker and a thiazide diuretic (water pill) used to treat high blood pressure (hypertension).Inderide is available in generic form. Inderal LA (propranolol)." Clin Sci 43 (1972): 385-91, 6. You can't miss doses. Try not to blink and do not rub the eye. The following are comments from users that experienced side effects while taking Milnacipran Hydrochloride Inderal “ ... have been contributing to weight gain and inability to lose weight, (lost 2lbs without trying in 3 weeks since cutting my dose), lethargy, heart palpitations, dry and itchy eyes … Parker WA "Propranolol-induced depression and psychosis." Insomnia. Purpose: A pilot randomized control trial to compare the efficacy and side effects of intralesional and oral propranolol in periorbital and eyelid capillary hemangiomas. Maisel A, Murray D, Lotz M, Rearden A, Irwin M, Michel M "Propranolol treatment affects parameters of human immunity." Feeling sleepy. Eye pain is found among people who take Propranolol hydrochloride, especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months. Pins and needles sensations. Grant RH, Keelan P, Kernohan RJ, et al "Multicenter trial of propranolol in angina pectoris." Propranolol is generally safe and side effects are usually mild and can be managed. are they safe over the long term? The likelihood of experiencing any of the side effects will depend on the individual; however, the more serious Propranolol side effects are very unusual, affecting less than one in 10,000 patients. Furthermore, with IVP injection the side effects of systemic route may be minimized as demonstrated with eye drop delivery of propranolol for treatment of retinal neovascularization. N Engl J Med 294 (1976): 930-6, 4. Connect with U.S. certified physicans to be prescribed and recieve propranolol directly to your door. i have nervous feeling when i am alone. Stomach Cramps 6. vitamins, herbal supplements, etc. Eur J Clin Pharmacol 48 (1995): 29-34. Br J Clin Pharmacol 24 (1987): s63-4, 20. Propranolol can be taken by adults and children. [Ref], Uncommon (0.1% to 1%): Renal insufficiency (related to lowering of systemic blood pressure)[Ref], There are reports of patients who experienced reversible renal insufficiency with no decline in systemic blood pressure, but these patients had preexisting renal disease. Clin Pharm 4 (1985): 214-8, 42. Propranolol may cause harmful effects in the baby if taken during pregnancy. Serious side effects of Propranolol are very unusual. lightheadedness, sleep problems (insomnia or unusual dreams ), vision changes, deceased sex drive, impotence, or. It is possible that your symptoms are related to the medication you are taking. Ann Pharmacother 39 (2005): 559-62, 38. Mentioned to my BP doctor and she immediately identified the above as side effects of porpranolol. Xanax users typically start being relieved of symptoms within an hour of taking the drug. O 0, 17. If you experience any of the above side effects from propranolol, it’s … Serious side effects are rare but could occur. Other Medicines. Morgan TO, Anavekar SN, Sabto J, et al "A comparison of beta adrenergic blocking drugs in the treatment of hypertension." Dry eyes; Nausea; Weakness or fatigue; Breathing problems; Changes in blood pressure; Vomiting; Although rare, more serious side efforts from propranolol can also occur. Greenblatt DJ, Koch-Weser J "Adverse reactions to propranolol in hospitalized medical patients: a report from the Boston Collaborative Drug Surveillance Program." Sobel BE "Propranolol and threatened myocardial infarction." if propranolol has been prescribed for depression why is one of the side effects actually depression. Suffered for 10 months, going to eye doctor after eye doctor and no longer being able to wear contacts. Reliant Pharmaceuticals, LLC., Bridgewater, NJ. Fogari R, Zoppi A, Corradi L, Preti P, Mugellini A, Lusardi P "beta-blocker effects on plasma lipids during prolonged treatment of hypertensive patients with hypercholesterolemia." Propranolol er is a moderately priced drug used to treat high blood pressure, heart muscle disease, and prevent chest pain caused by angina. 27. [Ref], Rare (less than 0.1%): Depression (dose dependent), hallucinations, psychoses, mood changes, confusion, memory loss[Ref], Rare (less than 0.1%): Anaphylaxis, contact dermatitis[Ref], Uncommon (0.1% to 1%): Reduction of platelet adhesiveness, thrombocytopenic purpura, nonthrombocytopenic purpura, agranulocytosis, eosinophilia[Ref], Frequency not reported: Stevens - Johnson syndrome, toxic epidermal necrolysis, exfoliative dermatitis, erythema multiforme, urticaria, purpura, alopecia, skin rashes, SLE-like reactions, Postmarketing reports: Dermatitis psoriasiform[Ref], Postmarketing reports: Enhanced immune system[Ref], Propranolol can enhance the immune system by causing an increase in the number of circulating T cells, increased interleukin-2 (IL-2) secretion, increased expression of IL-2 receptors, and increased lymphocyte production in response to the T cell mitogen Con A. Interestingly, NK (natural killer) cell activity may be decreased during propranolol therapy, although the number of circulating NK cells may remain unchanged. Methods: Twenty patients were prospectively randomized to two groups of ten each. Inderal (propranolol) is a beta blocker used to treat high blood pressure (hypertension), heart pain (angina), arrhythmia, and some neurologic conditions. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The phase IV clinical study is created by eHealthMe based on reports of 4,085 people who have side effects when taking Propranolol hydrochloride from the FDA, and is updated regularly. Dornhorst A, Powell SH, Pensky J "Aggravation by propranolol of hyperglycaemic effect of hydrochlorothiazide in type II diabetics without alteration of insulin secretion." Tell your doctor immediately if any of these unlikely but serious side effects occur: Sowinski KM, Burlew BS, Johnson JA "Racial differences in sensitivity to the negative chronotropic effects of propranolol in healthy men." Am Heart J 128 (1994): 1177-83, 34. Selected from data included with permission and copyrighted by First Databank, Inc. Am Heart J 110 (1985): 913-22, 8. Diabetes. [Ref], Very rare (less than 0.01%): Myasthenia gravis like syndrome or exacerbation of myasthenia gravis, Frequency not reported: Myopathy, myotonia[Ref], Very rare (less than 0.01%): Elevated liver function tests[Ref], Rare (less than 0.1%): Dry eyes, visual disturbances[Ref], 1. Am Heart J 86 (1973): 478-84, 2. These side effects are usually mild and short lived. A number of side effect of propranolol have been highlighted. SIDE EFFECTS: This medication may temporarily sting your eyes for a minute or two when you first use it. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings. Who can and cannot take propranolol. If you have diabetes you need to take extra care to measure your blood glucose levels regularly. Menu. Schoenberger JA, Croog SH, Sudilovsky A, et al "Self-reported side effects from antihypertensive drugs: a clinical trial." Along with its needed effects, a medicine may cause some unwanted effects. Kasiske BL, Ma JZ, Kalil RS, Louis TA "Effects of antihypertensive therapy on serum lipids." Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Concomitant administration with catecholamine-depleting drugs (e.g. Look downward and gently close your eye for 1 to 2 minutes. Propranolol can also cause other side effects. "Product Information. SIDE EFFECTS: This medication may temporarily sting your eyes for a minute or two when you first use it. [Ref], Rare (less than 0.1%): Dyspnea, worsening of reactive airways diseases, bronchospasm in patients with bronchial asthma or a history of asthmatic complaints (sometimes fatal)[Ref]. Choi KL, Wat MS, Ip TP, Kung AWC, Lam KSL "Phaeochromocytoma associated with myasthenia gravis precipitated by propranolol treatment." Holland OB, Kaplan NM "Propranolol in the treatment of hypertension." This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. May have potentiating effects on arterial conduction time and induce additive negative or inotropic effect with propafenone, amiodarone, quinidine, flecainide and Ca channel blockers. Imai Y, Watanabe N, Hashimoto J, Nishiyama A, Sakuma H, Sekino H, Omata K, Abe K "Muscle cramps and elevated serum creatine phosphokinase levels induced by beta-adrenoceptor blockers." Inderal (propranolol hydrochloride) is a beta-adrenergic receptor blocking agent used for control of hypertension. Immunopharmacology 22 (1991): 157-64, 51. blurred or loss of vision. body aches or pain. The most common side effects include: dry eyes; nausea; drowsiness; diarrhea; wheezing or … License: Except as otherwise noted, this work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.For commercial use or customized versions, please contact biobyte solutions GmbH.. Disclaimer: The content of this database of side effects (adverse drug reactions) is intended for educational and scientific research purposes only. Drug information provided by: IBM Micromedex. Arch Dermatol 121 (1985): 1326-7, 50. Side effects of combined medications may include any of the side effects of the drug types they contain. Propranolol side effects. Heart failure: Beta blockers, such as timolol, can slow down the heart rate and may cause severely decreased blood pressure. Chest 127 (2005): 818-24, 30. Ibsen H, Sederberg-Olsen P "Changes in glomerular filtration rate during long-term treatment with propranolol in patients with arterial hypertension." Side Effects What are the side effects of PropranoloL Hydrochloride ER?. Gastrointestinal. Non-selective beta-blockers, such as propranolol, are used with caution in patients with asthma and chronic obstructive pulmonary disease due to inhibition of bronchodilation. She heard a noise from upstairs, and it sounded what are blue pills used for as if she had hit something. Hair loss. Br J Clin Pharmacol 24 (1987): 615-20, 48. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Stomach cramps. Massa MC, Jason SM, Gradini R, Welykyj S "Lichenoid drug eruption secondary to propranolol." Horvath JS, Woolcock AJ, Tiller DJ, Donnelly P, Armstrong J, Caterson R "A comparison of metoprolol and propranolol on blood pressure and respiratory function in patients with hypertension." Do not rinse the dropper. bloody nose. Sasaki J, Kajiyama G, Kusukawa R, Mori H, Koga S, Takagi R, Tanaka N, Ogawa N, Arakawa K "Effect of bevantolol and propranolol on serum lipids in patients with essential hypertension." 14. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur while taking propranolol: If you experience any side effects, stop taking Etizolam + Propranolol right away. In Canada - Call your doctor for medical advice about side effects. Skip to: full site navigation. J Clin Psychiatry 47 (1986): 453-7, 43. Inability To Have An Erection 5. Skin rash. These side effects may include, but are not limited to, shortness of breath, dizziness, lightheadedness, rash, or slow heartbeat. Postgrad Med J 50 (1974): 253-9, 11. Propranolol slows down a person's heart rate and makes it easier for the heart to beat. Give propranolol solution at around the same time(s) every day. Like all medicines, propranolol can cause side effects, although not everyone gets them. The important thing is to tell your prescriber or pharmacist if you are having problems with your medicine. Other brands: Inderal, Inderal LA, Inderal XL, Hemangeol, InnoPran XL, amlodipine, aspirin, metoprolol, lisinopril, losartan, furosemide, hydrochlorothiazide, carvedilol, atenolol, diltiazem. Am J Hypertens 3 (1990): 123-32. Some investigators have reported a 4% to 9% reduction in total energy expenditure and a 25% reduction in thermogenic response to food during beta-blocker treatment. Levinson DF, Acquaviva J "Exacerbation of panic disorder during propranolol therapy." Check with your doctor immediately if any of the following side effects occur while taking propranolol: Some side effects of propranolol may occur that usually do not need medical attention. Inderal (Propranolol) is good for treating many heart problems and other problems in the body, but it has more side effects than other beta blockers. Use of a nonselective beta-blocker like propranolol may at least blunt cardiac output in some patients, especially those with preexisting left ventricular systolic dysfunction and during exertion. Stephen SA "Unwanted effects of propranolol." Interestingly, the fall was not related to smoking or to atopic status, suggestive of resting beta-adrenergic bronchodilator activity in nonasthmatic subjects. J Nerv Ment Dis 173 (1985): 118-9, 45. The same side effects reported with oral medications from the family known as beta-blockers (e.g., timolol, propranolol, metoprolol) may occur with the eye drops. Propranolol is a prescription medication with the potential for serious side effects, and its usage should not be taken lightly. Propranolol and other beta blockers can cause you to develop dry eyes, potentially resulting in eye irritation. For Propranolol users, the results can be even quicker. it is available in generic and brand versions. Br Med J 1 (1969): 7-16, 25. Am J Med 66 (1979): 405-10, 9. Higher doses of propranolol work to control heart arhrythmias. [Ref], Frequency not reported: Male impotence, Peyronie's disease[Ref], The mechanism by which propranolol induces weight gain is unknown. Bauer JH, Brooks CS "The long-term effect of propranolol therapy on renal function." This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Diarrhea 3. Clin Pharmacol Ther 57 (1995): 678-83, 5. Martinez-Mir I, Navarro-Badenes J, Palop V, Morales-Olivas FJ, Rubio E "Weight gain induced by long-term propranolol treatment." Vision may be temporarily blurred or unstable after applying drops. WebMD does not provide medical advice, diagnosis or treatment. Propranolol was patented in 1962 and approved for medical use in 1964. blood in the urine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Propranolol has been associated with significant increases in serum triglycerides, fasting blood glucose, and LDL and VLDL cholesterol, and significant decreases in HDL cholesterol. drugs.com, webmd: Propranalol has been available for many years and there is data on long term safety and side effects. Propranolol is generally safe and side effects are usually mild and can be managed. Drugs 7 (1974): 118-29, 7. Feel Like Throwing Up 4. Cunnane JG, Blackwood GW "Psychosis with propanolol: still not recognized?" See the section Side Effects on pages 2 and 3. Darga LL, Hakim MJ, Lucas CP, Franklin BA "Comparison of the effects of guanadrel sulfate and propranolol on blood pressure, functional capacity, serum lipoproteins and glucose in systemic hypertension." how can i see the long-term efficacy (and any side effects) of propranolol and related drugs? Rare cases of psychoses associated with propranolol have been reported. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. As with other serious side effects of propranolol, if you experience severe nausea, vomiting or diarrhea, you should contact your doctor as soon as possible. It was not. The main side effects of propranolol are feeling dizzy or tired, cold hands or feet, difficulties sleeping and nightmares. Headache.